An information handling system touchpad includes an application area with a display to present control icons of an application executing on the information handling system, such as camera and microphone icons to control camera and microphone functions of a videoconference application. The touchpad dynamically scales between a first configuration that accepts cursor inputs at the full touch detection surface area and a second configuration that limits cursor inputs to touches in a first portion of the touch detection surface and presents control icons in a second portion, such as by applying different touch analysis logic to end user touches in the first and second portions.