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US Patent 11981726 Antibody neutralizing human respiratory syncytial virus

Patent 11981726 was granted and assigned to Merck Sharp & Dohme Limited on May, 2024 by the United States Patent and Trademark Office.

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Patent attributes

Patent Applicant

Merck Sharp & Dohme Limited

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Current Assignee

Merck Sharp & Dohme Limited

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Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

Zhifeng Chen0

Kalpit A. Vora0

Hua-Poo Su0

Lan Zhang0

Kara S. Cox0

Aimin Tang0

Daniel DiStefano0

Date of Patent

May 14, 2024

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Patent Application Number

180651720

Date Filed

December 13, 2022

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Patent Citations

US Patent 7867497 Monoclonal antibodies to respiratory syncytial virus and uses therefor

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US Patent 8568726 RSV specific binding molecule

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US Patent 8221759 Neutralizing monoclonal antibodies to respiratory syncytial virus

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US Patent 7029872 Methods for producing modified glycoproteins

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US Patent 7125689 Method for rendering streptokinase less immunogenic to a human

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US Patent 7364737 Human neutralizing monoclonal antibodies to respiratory syncytial virus

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US Patent 7449308 Combinatorial DNA library for producing modified N-glycans in lower eukaryotes

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US Patent 7488477 Neutralizing monoclonal antibodies to respiratory syncytial virus

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Patent Primary Examiner

Barry A Chestnut

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CPC Code

0

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Patent abstract

The present invention relates to monoclonal antibodies which have high anti-RSV neutralizing titers. The invention further provides for isolated nucleic acids encoding the antibodies of the invention and host cells transformed therewith. The invention yet further provides for diagnostic, prophylactic and therapeutic methods employing the antibodies and nucleic acids of the invention, particularly as a passive immunotherapy agent in infants and the elderly.

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