A shelf and ladder combination includes two support rod units, partition plates connected between the support rod units, a cross bar, two main connecting brackets connecting the cross bar to the support rod units, and a ladder unit. The ladder unit includes two ladder legs, at least one fixing unit, and a plurality of rungs connected between the ladder legs. Each ladder leg has a first end portion adjacent to the crossbar, and a second end portion opposite to the first end portion. The at least one fixing unit is sleeved on the crossbar, is slidable along the crossbar, and is connected to the first end portion of one of the ladder legs.