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US Patent 11993642 Trivalent, bispecific antibodies

Patent 11993642 was granted and assigned to Hoffmann-La Roche Limited on May, 2024 by the United States Patent and Trademark Office.

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Patent attributes

Patent Applicant

Hoffmann-La Roche Limited

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Current Assignee

Hoffmann-La Roche Limited

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Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

Christian Klein0

Claudio Sustmann0

Eike Hoffmann0

Ekkehard Moessner0

Juergen Michael Schanzer0

Rebecca Croasdale0

Pablo Umana0

Ulrich Brinkmann0

Date of Patent

May 28, 2024

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Patent Application Number

164134690

Date Filed

May 15, 2019

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Patent Citations

US Patent 7355008 Identification and engineering of antibodies with variant Fc regions and methods of using same

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US Patent 6897044 Production of tetravalent antibodies

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US Patent 6946292 Cells producing antibody compositions with increased antibody dependent cytotoxic activity

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US Patent 7125978 Promoter for regulating expression of foreign genes

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US Patent 7129330 Multivalent antibody constructs

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US Patent 7332581 Polypeptide variants with altered effector function

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US Patent 9879095 Bispecific antibodies comprising a disulfide stabilized-Fv fragment

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US Patent 9890204 Trivalent, bispecific antibodies

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Patent Primary Examiner

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Patent abstract

The present invention relates to trivalent, bispecific antibodies, methods for their production, pharmaceutical compositions containing the antibodies, and uses thereof.

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