Patent attributes
A method for augmenting a void or treating a wound in a body cavity involves applying a three-dimensional, resorbable collagen scaffold derived from a vascularized portion of a perfusion-decellularized mammalian tissue or organ to the site of the void or body cavity. This application allows for cellular infiltration, integration, or remodeling of the surrounding body tissue into one or more vascular pathways of the scaffold. The scaffold is applied in a manner that ensures at least three surfaces of the scaffold make contact with the surrounding body tissue. The scaffold includes a plurality of pores, resulting in a surface area significantly larger than a poreless scaffold of the same outer dimensions. The method can also include placing milled fibers to any undermining or irregularities in the void or cavity before applying the scaffold.