Is a
Patent attributes
Patent Applicant
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Yi Zhang0
Michael S. Singer0
C. Andrew Stewart0
Murat V. Kalayoglu0
Metin Kurtoglu0
Date of Patent
June 4, 2024
0Patent Application Number
175409470
Date Filed
December 2, 2021
0Patent Citations
...
Patent Primary Examiner
Patent abstract
Provided herein are chimeric antigen receptors (CARs), such as those specific for BCMA, that have improved properties, including increased CAR T cell binding to BCMA and improved CAR T cell killing of BCMA-expressing cancer cells. Use of the CARs in immune cells (e.g., T cells), compositions (e.g., CARs and nucleic acid constructs encoding the same), and methods are also contemplated.
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