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US Patent 11999802 Compositions and methods for selective protein degradation

Patent 11999802 was granted and assigned to Novartis on June, 2024 by the United States Patent and Trademark Office.

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Patent Applicant

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Current Assignee

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Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

Jonathan M. Solomon0

James E. Bradner0

Seth Carbonneau0

Marc Horst Peter Hild0

Nathan Thomas Ross0

Carleton Proctor Goold0

Rohan Eric John Beckwith0

Carla Patricia Pinto Guimaraes0

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Date of Patent

June 4, 2024

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Patent Application Number

167570260

Date Filed

October 18, 2018

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Patent Primary Examiner

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Patent abstract

The invention provides compositions including a fusion polypeptide and methods for making a fusion polypeptide that includes a COF1/CRBN-binding polypeptide, COF2/CRBN-binding polypeptide, or COF3/CRBN-binding polypeptide and a heterologous polypeptide of interest.

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