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US Patent 11999951 Massively parallel contiguity mapping

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 US Patent 11999951 Massively parallel contiguity mapping

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Patent abstract

Contiguity information is important to achieving high-quality de novo assembly of mammalian genomes and the haplotype-resolved resequencing of human genomes. The methods described herein pursue cost-effective, massively parallel capture of contiguity information at different scales.

Infobox
Is a
Patent
Patent
0
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
0
Patent Number
119999510
Patent Inventor Names
Akash Kumar0
Andrew Colin Adey0
Cho li Lee0
Jacob Otto Kitzman0
Jay Ashok Shendure0
Jerrod Joseph Schwartz0
Joseph Brian Hiatt0
Date of Patent
June 4, 2024
0
Patent Application Number
177165390
Date Filed
April 8, 2022
0
Patent Citations
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US Patent 7115400 Methods of nucleic acid amplification and sequencing
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US Patent 7211414 Enzymatic nucleic acid synthesis: compositions and methods for altering monomer incorporation fidelity
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US Patent 7244559 Method of sequencing a nucleic acid
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US Patent 7315019 Arrays of optical confinements and uses thereof
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US Patent 7329492 Methods for real-time single molecule sequence determination
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US Patent 7399590 Recombinase polymerase amplification
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US Patent 7405281 Fluorescent nucleotide analogs and uses therefor
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US Patent 7537897 Molecular counting
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US Patent 7582420 Multiplex nucleic acid reactions
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US Patent 7595883 Biological analysis arrangement and approach therefor
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US Patent 7611869 Multiplexed methylation detection methods
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US Patent 7670810 Methods and compositions for whole genome amplification and genotyping
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US Patent 7696340 Nucleotide and amino acid sequences from
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US Patent 7741463 Method of preparing libraries of template polynucleotides
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US Patent 8003354 Multiplex nucleic acid reactions
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US Patent 8563477 Modified molecular arrays
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US Patent 8829171 Linking sequence reads using paired code tags
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US Patent 9074251 Linking sequence reads using paired code tags
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US Patent 9644198 RNase H-based assays utilizing modified RNA monomers
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US Patent 9644199 Immobilized transposase complexes for DNA fragmentation and tagging
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US Patent 10246746 Preserving genomic connectivity information in fragmented genomic DNA samples
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US Patent 10457936 Massively parallel contiguity mapping
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US Patent 10550426 Method for detecting methylated DNA
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US Patent 11299730 Massively parallel contiguity mapping
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US Patent 6846658 Method for cloning and producing the Msel restriction endonuclease
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US Patent 7001792 Ultra-fast nucleic acid sequencing device and a method for making and using the same
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US Patent 7057026 Labelled nucleotides
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Patent Primary Examiner
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Sahana S Kaup
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CPC Code
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C12N 15/1093
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Y02P 20/582
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