Patent 12005061 was granted and assigned to Aldeyra Therapeutics on June, 2024 by the United States Patent and Trademark Office.
The present disclosure provides formulations of methotrexate for ocular administration, including intravitreal administration, and use of the formulations for treating proliferative vitreoretinopathy (PVR), intraocular lymphoma (e.g., PVRL), and intraocular inflammation.