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US Patent 12005127 DNA-PK inhibitors

Patent 12005127 was granted and assigned to Vertex Pharmaceuticals on June, 2024 by the United States Patent and Trademark Office.

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Patent attributes

Patent Applicant

Vertex Pharmaceuticals

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Current Assignee

Vertex Pharmaceuticals

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Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

John Patrick Maxwell0

Steven M. Ronkin0

Qing Tang0

Jinwang Xu0

Paul S. Charifson0

Mark A. Morris0

Kevin M. Cottrell0

Katrina Lee Jackson0

Date of Patent

June 11, 2024

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Patent Application Number

169624420

Date Filed

January 16, 2019

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Patent Citations

US Patent 7153949 Nucleic acid encoding poly-zinc finger proteins with improved linkers

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US Patent 6903185 Poly zinc finger proteins with improved linkers

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US Patent 7030215 Position dependent recognition of GNN nucleotide triplets by zinc fingers

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US Patent 7067317 Regulation of angiogenesis with zinc finger proteins

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US Patent 7070934 Ligand-controlled regulation of endogenous gene expression

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US Patent 7074596 Synthesis and use of anti-reverse mRNA cap analogues

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US Patent 8153773 Synthesis and use of anti-reverse phosphorothioate analogs of the messenger RNA cap

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US Patent 8404681 Xanthones, thioxanthones and acridinones as DNA-PK inhibitors

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Patent Primary Examiner

D Margaret M Seaman

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CPC Code

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Patent abstract

The present invention relates to compounds useful as inhibitors of DNA-PK. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various diseases, conditions, or disorders.

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