Is a
Patent attributes
Patent Applicant
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Stephen Howard Thorne0
Mingrui Zhang0
Date of Patent
June 25, 2024
0Patent Application Number
180802530
Date Filed
December 13, 2022
0Patent Citations
...
Patent Primary Examiner
Patent abstract
The present disclosure provides for recombinant oncolytic viruses with gene deletions or insertions which result in downregulation of Major Histocompatibility Complex class I and alternatively or additively upregulation of Major Histocompatibility Complex class II. Immunologic and pharmaceutical compositions comprising these recombinant viruses and methods of using these compositions are also presented.
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