US Patent 12016908 Compositions and methods for treating hemoglobinopathies
Patent 12016908 was granted and assigned to Beam Therapeutics on June, 2024 by the United States Patent and Trademark Office.
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US Patent 12016908 Compositions and methods for treating hemoglobinopathies
Article
Patent abstract
The present invention features compositions and methods for editing deleterious mutations associated with hemoglobinopathies, such as sickle cell disease (SCD). In particular embodiments, the invention provides methods for correcting mutations in a beta globin polynucleotide using modified adenosine base editors termed “ABE8” having unprecedented levels (e.g., >60-70%) of efficiency.
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Patent Applicant
Current Assignee
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Patent Number
Patent Inventor Names
Bernd Zetsche0
David A. Born0
Ian Slaymaker0
Michael Packer0
Nicole Gaudelli0
Seung-Joo Lee0
Yi Yu0
Date of Patent
June 25, 2024
0Patent Application Number
178151280
Date Filed
July 26, 2022
0Patent Citations
Patent Primary Examiner
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