Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Yang Feng0
Reuben Benjamin0
Michel Sadelain0
Dimiter S. Dimitrov0
Date of Patent
June 25, 2024
0Patent Application Number
169122910
Date Filed
June 25, 2020
0Patent Citations
Patent Primary Examiner
Patent abstract
The presently disclosed subject matter provides for methods and compositions for treating cancer (e.g., multiple myeloma). It relates to anti-CD56 antibodies, chimeric antigen receptors (CARs) that specifically target human CD56, and immunoresponsive cells comprising such CARs. The presently disclosed CD56-specific CARs have enhanced immune-activating properties, including anti-tumor activity.
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