Is a
Patent attributes
Patent Applicant
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Barbara Sanders0
Christian Maine0
Roland Zahn0
Manuel Alejandro Sepulveda0
Selina Khan0
Jenifer Lum0
Vinod Krishna0
Ricardo Attar0
...
Date of Patent
June 25, 2024
0Patent Application Number
170974580
Date Filed
November 13, 2020
0Patent Citations
...
Patent Primary Examiner
Patent abstract
Provided are vaccines, polypeptides and polynucleotides based on mutant CALR and JAK2 sequences, vectors, host cells, viruses, and methods of making and using them. The disclosure also provides methods of inducing an immune response and methods of treating, preventing, reducing a risk of onset or delaying the onset of a clinical condition characterized by an expression of JAK2V617F or CALR exon 9 mutant, or both JAK2V617F and CALR exon 9 mutant, wherein the method comprises a plurality of administrations of any of the compositions comprising polynucleotides, polypeptides or vectors disclosed herein.
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