US Patent 12060407 IL-15/IL-15Ralpha based conjugates purification method
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US Patent 12060407 IL-15/IL-15Ralpha based conjugates purification method
Article
Patent abstract
The present invention relates to a method for preparing a composition comprising monomeric conjugates from a sample, said conjugate comprising (a) a polypeptide comprising the amino acid sequence of interleukin 15 or derivatives thereof, and (b) a polypeptide comprising the amino acid sequence of the sushi domain of IL-15Rα or derivatives thereof; wherein said method comprises the use of anion-exchange chromatography followed by a hydrophobic interaction chromatography; and to a pharmaceutical composition which can be obtained by such a method.
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Patent Inventor Names
David Bechard0
Guy De Martynoff0
Date of Patent
August 13, 2024
0Patent Application Number
170258930
Date Filed
September 18, 2020
0Patent Citations
Patent Primary Examiner
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