Is a
Patent attributes
Patent Applicant
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Paul Conroy0
Stephen Hearty0
Lok Hang Mak0
Date of Patent
August 20, 2024
0Patent Application Number
185424410
Date Filed
December 15, 2023
0Patent Citations
Patent Primary Examiner
CPC Code
Patent abstract
The present disclosure provides T cell receptor (TCR) fusion proteins comprising a TCR that binds to a GVYDGREHTV (SEQ ID NO:34) HLA-A*02 complex that is covalently linked to a T cell engaging domain that binds a protein expressed on a cell surface of a T cell and an antibody Fc domain, as well as polynucleotides, vectors, kits, host cells, pharmaceutical compositions, methods, and uses related thereto.
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