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US Patent 12065478 HER2-targeting antigen binding molecules comprising 4-1BBL

Patent 12065478 was granted and assigned to Hoffmann-La Roche Limited on August, 2024 by the United States Patent and Trademark Office.

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Patent abstract

The invention relates to Her2 targeting 4-1BB agonists, in particular 4-1BBL trimer-containing antigen binding molecules comprising at least one antigen binding domain capable of specific binding to Her2 and their use in the treatment of cancer as well as their use in combination with T-cell activating anti-CD3 bispecific antibodies.

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