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US Patent 12071456 Extended recombinant polypeptides and compositions comprising same

Patent 12071456 was granted and assigned to Amunix Pharmaceuticals, Inc. on August, 2024 by the United States Patent and Trademark Office.

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Patent attributes

Patent Applicant

Amunix Pharmaceuticals, Inc.

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Current Assignee

Amunix Pharmaceuticals, Inc.

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Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

Jeffrey L. Cleland0

Benjamin Spink0

Nathan Geething0

Wayne To0

Volker Schellenberger0

Chia-wei Wang0

Willem P. Stemmer0

Joshua Silverman0

Date of Patent

August 27, 2024

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Patent Application Number

171504260

Date Filed

January 15, 2021

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Patent Citations

US Patent 7041635 Factor VIII polypeptide

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US Patent 7045318 Recombinant fusion proteins to growth hormone and serum albumin

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US Patent 7138505 Factor VIII:C nucleic acid molecules

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US Patent 7199223 Polymer-factor VIII moiety conjugates

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US Patent 7235626 Structured peptide scaffold for displaying turn libraries on phage

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US Patent 7276475 Remodeling and glycoconjugation of peptides

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US Patent 7294513 Method and apparatus for characterizing solutions of small particles

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US Patent 7329640 Method of treatment of hemorrhagic disease using a factor VIIa/tissue factor inhibitor

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Patent Primary Examiner

Randall L Beane

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CPC Code

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Patent abstract

The present invention relates to compositions comprising biologically active proteins linked to extended recombinant polypeptide (XTEN), isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of using such compositions in treatment of glucose-related diseases, metabolic diseases, coagulation disorders, and growth hormone-related disorders and conditions.

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