US Patent 12071638 Variants of terminal deoxynucleotidyl transferase and uses thereof
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US Patent 12071638 Variants of terminal deoxynucleotidyl transferase and uses thereof
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Patent abstract
The present invention relates to variants of Terminal deoxynucleotidyl Transferase (TdT), each of which (i) has an amino acid sequence similarity to SEQ ID NO: 2. 11, 13, 15, 17, 19, 21, 23, 25, 27, 29, 31, 33 or 35 with corresponding amino acid substitutions, (ii) is capable of synthesizing a nucleic acid fragment without a template and (iii) is capable of incorporating a modified nucleotide into the nucleic acid fragment.
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Patent Inventor Names
Elise Champion0
Marc Delarue0
Mikhael Soskine0
Thomas Ybert0
Date of Patent
August 27, 2024
0Patent Application Number
175446470
Date Filed
December 7, 2021
0Patent Citations
Patent Primary Examiner
CPC Code
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