Patent 12076348 was granted and assigned to MIMEDX GROUP, INC. on September, 2024 by the United States Patent and Trademark Office.
Provided herein are micronized placental compositions composed of micronized placental tissue component, such as amnion or chorion and/or filler bound to one or more chelating agents, which in turn are optionally bound, reversibly, to pharmacologically active metal ions. Further provided are methods of making and using the placental compositions. The compositions have numerous therapeutic applications.