US Patent 12076398 Anti-PD1 monoclonal antibody, pharmaceutical composition thereof and use thereof
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US Patent 12076398 Anti-PD1 monoclonal antibody, pharmaceutical composition thereof and use thereof
Article
Patent abstract
An anti-PDl (programmed cell death 1) monoclonal antibody or an antigen-binding fragment thereof, a pharmaceutical composition thereof and use thereof. The heavy chain variable region of the monoclonal antibody comprises CDRs (complementary determining region) of amino acid sequences as shown in SEQ ID NO:9-11; and/or the light chain variable region of the monoclonal antibody comprises CDRs of amino acid sequences as shown in SEQ ID NO: 12-14. The monoclonal antibody can bind to PDl specifically, relieve immunosuppression of PDl on an organism specifically and activate T lymphocytes.
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Patent Jurisdiction
Patent Number
Patent Inventor Names
Baiyong Li0
Peng Zhang0
Yu Xia0
Zhongmin Maxwell Wang0
Date of Patent
September 3, 2024
0Patent Application Number
163270830
Date Filed
August 22, 2017
0Patent Citations
Patent Primary Examiner
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