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US Patent 12076411 Anti-HER2 antibody-maytansine conjugates and methods of use thereof

Patent 12076411 was granted and assigned to Redwood Bioscience on September, 2024 by the United States Patent and Trademark Office.

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Patent attributes

Patent Applicant

Redwood Bioscience

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Current Assignee

Redwood Bioscience

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Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

Albert W. Garofalo0

Jesse M. McFarland0

Romas Alvydas Kudirka0

Robyn M. Barfield0

Aaron Edward Albers0

Gregory W. deHart0

Penelope M. Drake0

David Rabuka0

Date of Patent

September 3, 2024

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Patent Application Number

173830760

Date Filed

July 22, 2021

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Patent Citations

US Patent 9540438 Aldehyde-tagged immunoglobulin polypeptides and methods of use thereof

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US Patent 11097013 Anti-HER2 antibody-maytansine conjugates and methods of use thereof

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US Patent 9833515 Hydrazinyl-indole compounds and methods for producing a conjugate

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US Patent 7585491 Immunoconjugates with an intracellularly-cleavable linkage

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US Patent 7985783 Aldehyde tags, uses thereof in site-specific protein modification

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US Patent 8729232 Aldehyde tags, uses thereof in site-specific protein modification

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US Patent 9310374 Hydrazinyl-indole compounds and methods for producing a conjugate

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US Patent 9493413 Hydrazinyl-pyrrolo compounds and methods for producing a conjugate

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Patent Primary Examiner

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CPC Code

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Patent abstract

The present disclosure provides anti-HER2 antibody-maytansine conjugate structures. The disclosure also encompasses methods of production of such conjugates, as well as methods of using the same.

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