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US Patent 12077790 Optimized binuclease fusions and methods

Patent 12077790 was granted and assigned to Resolve Therapeutics on September, 2024 by the United States Patent and Trademark Office.

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Patent abstract

The invention provides for optimized binuclease fusion proteins with increased pharmacokinetic properties. The optimized binuclease fusion proteins of the invention two or more nuclease domains (e.g., RNase and DNase domain) operably coupled to an Fc domain. The invention also provides methods of treating or preventing a condition associated with an abnormal immune response.

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