Patent 12084420 was granted and assigned to Volastra Therapeutics on September, 2024 by the United States Patent and Trademark Office.
The present disclosure relates generally to inhibitors of KIF18A, compositions thereof, and methods of using the compounds and compositions thereof. More specifically, the present disclosure relates to indoline inhibitors of KIF18A and methods of their use for treating disease mediated by KIF18A, such as cancer.