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US Patent 12084497 SIRP1α targeted chimeric proteins and uses thereof

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Is a

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Patent attributes

Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

Jan Tavernier0

Nikolai Kley0

Date of Patent

September 10, 2024

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Patent Application Number

172662500

Date Filed

August 8, 2019

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Patent Citations

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US Patent 8980267 Engineered antibody-interferon mutant fusion molecules

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US Patent 9139634 Interferon-antibody fusion proteins demonstrating potent apoptotic and anti-tumor activities

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US Patent 9352037 Compositions and methods to enhance the immune system

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US Patent 9492562 Targeted human-interferon fusion proteins

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Patent Primary Examiner

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CPC Code

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Patent abstract

The present invention relates, in part, to agents that bind SIRP1α and their use as diagnostic and therapeutic agents. The present invention further relates to pharmaceutical compositions comprising the SIRP1α targeting moiety and their use in the treatment of various diseases.

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