Is a
Patent attributes
Patent Applicant
Patent Jurisdiction
Patent Number
Patent Inventor Names
Annick Goergler0
Eric Andre Kusznir0
Fabian Dey0
Moreno Attilio Wichert0
Roger Norcross0
Adrian Britschgi0
Date of Patent
September 17, 2024
0Patent Application Number
178787530
Date Filed
August 1, 2022
0Patent Citations
...
Patent Primary Examiner
Patent abstract
The present invention provides dihydroquinolinone compounds which bind to the ubiquitously expressed E3 ligase protein cereblon (CRBN) and alter the substrate specificity of the CRBN E3 ubiquitin ligase complex, resulting in breakdown of intrinsic downstream proteins. The disclosed compounds are useful for the treatment of cancer.
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