Is a
Patent attributes
Patent Applicant
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Rinse Klooster0
Mark Throsby0
Pieter Fokko van Loo0
Cornelis Adriaan de Kruif0
Tomoya Tezuka0
Takuya Shimbo0
Shiro Shibayama0
Date of Patent
September 17, 2024
0Patent Application Number
173668780
Date Filed
July 2, 2021
0Patent Citations
...
Patent Primary Examiner
Patent abstract
A bispecific antibody which is capable of specifically binding to PD-1 and CD3 is disclosed. The bispecific antibody is suitable for preventing, suppressing symptom progression or recurrence of, and/or treating autoimmune diseases. Also disclosed is a formulation which can reduce occurrence of adverse infusion reactions or adverse reaction called cytokine release syndrome. The bispecific antibody has the feature to allow interaction between PD-1 and PD-L1 as its ligand, contributes enhancement or duration of its effects.
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