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US Patent 12104185 PH20 polypeptide variants, formulations and uses thereof

Patent 12104185 was granted and assigned to Halozyme, Inc. on October, 2024 by the United States Patent and Trademark Office.

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Contents

Is a
Patent
Patent
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Patent attributes

Patent Applicant
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Halozyme, Inc.
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Current Assignee
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Halozyme, Inc.
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
121041850
Patent Inventor Names
H. Michael Shepard0
Robert James Connor0
Ge Wei0
Qiping Zhao0
Date of Patent
October 1, 2024
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Patent Application Number
185994280
Date Filed
March 8, 2024
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Patent Citations
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US Patent 7829081 Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminoglycanases
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US Patent 7105330 Human plasma hyaluronidase
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US Patent 7279457 Rapid acting drug delivery compositions
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US Patent 7585940 Muteins of human tear lipocalin
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US Patent 7767429 Soluble hyaluronidase glycoprotein (sHASEGP), process for preparing the same, uses and pharmaceutical compositions comprising thereof
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US Patent 7781397 Human plasma hyaluronidase
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US Patent 8343487 Large-scale production of soluble hyaluronidase
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US Patent 8431124 Methods for treating a disease characterized by an excess of hyaluronan by administering a soluble hyaluronidase glycoprotein (sHASEGP)
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Patent Primary Examiner
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Louise W Humphrey
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CPC Code
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Y02A 50/30
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C12Y 302/01035
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A61K 9/0019
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A61K 38/28
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A61K 38/47
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A61K 45/06
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A61K 47/10
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A61K 38/00
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Patent abstract

Modified PH20 hyaluronidase polypeptides, including modified polypeptides that exhibit increased stability and/or increased activity, are provided. Also provided are compositions and formulations and uses thereof.

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