US Patent 12104188 Modified caspase-9 polypeptides and methods of use thereof
Patent 12104188 was granted and assigned to Allogene Therapeutics on October, 2024 by the United States Patent and Trademark Office.
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US Patent 12104188 Modified caspase-9 polypeptides and methods of use thereof
Article
Patent abstract
Provided herein are modified caspase-9 polypeptides, and chimeric caspase-9 proteins containing the modified caspase-9 polypeptides. The disclosure further provides polynucleotides encoding these proteins, engineered host cells containing these polynucleotides and proteins, including host cells that co-express a chimeric antigen receptor, and methods of making and using the same.
Infobox
Is a
Patent Applicant
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Meritxell Galindo Casas0
Thomas John Van Blarcom0
Date of Patent
October 1, 2024
0Patent Application Number
177162530
Date Filed
April 8, 2022
0Patent Citations
Patent Primary Examiner
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