US Patent 12104207 Genomewide unbiased identification of DSBs evaluated by sequencing (GUIDE-Seq)

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Patent

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Patent Jurisdiction

United States Patent and Trademark Office

Patent Number

121042070

Patent Inventor Names

J. Keith Joung0

Shengdar Tsai0

Date of Patent

October 1, 2024

Patent Application Number

167082320

Date Filed

December 9, 2019

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US Patent 8071312 Methods for producing and using stem-loop oligonucleotides

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US Patent 8399199 Use of stem-loop oligonucleotides in the preparation of nucleic acid molecules

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US Patent 8420319 Asymmetric adapter library construction

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US Patent 8697359 CRISPR-Cas systems and methods for altering expression of gene products

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Patent abstract

Unbiased, genomewide and highly sensitive methods for detecting mutations, e.g., off-target mutations, induced by engineered nucleases.

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US Patent 12104207 Genomewide unbiased identification of DSBs evaluated by sequencing (GUIDE-Seq)

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