Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Aviv Regev0
Rebecca H. Herbst0
Ramnik Xavier0
Christopher Smillie0
Jose Ordovas-Montanes0
Moshe Biton0
Alexander K. Shalek0
Date of Patent
October 1, 2024
0Patent Application Number
166320180
Date Filed
July 17, 2018
0Patent Citations
0
0
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Patent Primary Examiner
CPC Code
Patent abstract
The present invention provides for a human cell atlas of the colon from healthy and diseased subjects. The atlas was obtained by single sequencing of about 117,000 cells. The present invention discloses novel markers for cell types. Moreover, genes associated with disease are identified in the colon and colon specific cell types. The invention provides for diagnostic assays based on gene markers and cell composition, as well as target cell types that express genes associated with disease. Finally, disclosed are novel cell types and methods of quantitating, detecting and isolating the cell types.
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