Systems and methods for seamless pairing of wireless devices in hoteling environments are described. In an embodiment, an Information Handling System (IHS), may include a processor and a memory coupled to the processor, the memory having program instructions stored thereon that, upon execution, cause the IHS to: in response to a temporary reservation of one of a plurality of workspaces, receive data associated with a peripheral device located in the workspace; pre-pair the peripheral device to the IHS based upon the data in anticipation of the IHS having reached the workspace; and in response to a determination that the IHS has reached the workspace, complete a pairing of the peripheral device to the IHS.