Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Da Duan0
Oscar Alvizo0
Jeffrey C. Moore0
Deeptak Verma0
Jay H. Russell0
Auric Anthony Sowell-Kantz0
Keith A. Canada0
Jovana Nazor0
...
Date of Patent
October 8, 2024
0Patent Application Number
174902150
Date Filed
September 30, 2021
0Patent Citations
...
Patent Primary Examiner
CPC Code
Patent abstract
The present invention provides engineered purine nucleoside phosphorylase (PNP) enzymes, polypeptides having PNP activity, and polynucleotides encoding these enzymes, as well as vectors and host cells comprising these polynucleotides and polypeptides. Methods for producing PNP enzymes are also provided. The present invention further provides compositions comprising the PNP enzymes and methods of using the engineered PNP enzymes. The present invention finds particular use in the production of pharmaceutical compounds.
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