Is a
Patent attributes
Patent Applicant
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Joshua Delaney0
Meiliana Tjandra0
Jill Herschleb0
Shalini Gohil0
Adam Lowe0
Albert Kim0
Date of Patent
October 15, 2024
0Patent Application Number
185035640
Date Filed
November 7, 2023
0Patent Citations
...
Patent Primary Examiner
Patent abstract
The present disclosure provides compositions and methods for using fixed biological samples in partition-based assays. In at least one embodiment, the disclosure provides a composition comprising a fixed biological sample and an un-fixing agent contained in a partition, such as a discrete droplet. In some embodiments, the disclosure provides un-fixing agent compounds capable of catalytically cleaving crosslinks in fixed biological samples, particularly crosslinked nucleic acids, such as RNA.
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