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US Patent 12121524 DNA-PK inhibitors

Patent 12121524 was granted and assigned to Vertex Pharmaceuticals on October, 2024 by the United States Patent and Trademark Office.

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Is a
Patent
Patent
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Patent attributes

Patent Applicant
Vertex Pharmaceuticals
Vertex Pharmaceuticals
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Current Assignee
Vertex Pharmaceuticals
Vertex Pharmaceuticals
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
121215240
Patent Inventor Names
Sudipta Mahajan0
Diego Sebastian D'Astolfo0
Marc Saul Weinberg0
Date of Patent
October 22, 2024
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Patent Application Number
169624410
Date Filed
January 16, 2019
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Patent Citations
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US Patent 7070934 Ligand-controlled regulation of endogenous gene expression
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US Patent 6903185 Poly zinc finger proteins with improved linkers
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US Patent 7030215 Position dependent recognition of GNN nucleotide triplets by zinc fingers
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US Patent 7067317 Regulation of angiogenesis with zinc finger proteins
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US Patent 8932814 CRISPR-Cas nickase systems, methods and compositions for sequence manipulation in eukaryotes
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US Patent 8945839 CRISPR-Cas systems and methods for altering expression of gene products
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US Patent 8993233 Engineering and optimization of systems, methods and compositions for sequence manipulation with functional domains
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US Patent 8999641 Engineering and optimization of systems, methods and compositions for sequence manipulation with functional domains
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...
Patent Primary Examiner
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Thane Underdahl
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CPC Code
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C12N 9/12
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C12Y 207/11011
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Patent abstract

The present invention relates to compounds useful as inhibitors of DNA-PK. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various diseases, conditions, or disorders.

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