Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Samuel Achilefu0
Avik Som0
Rui Tang0
Duanwen Shen0
Christopher Egbulefu0
Kexian Liang0
Partha Karmakar0
Baogang Xu0
...
Date of Patent
October 22, 2024
0Patent Application Number
183274550
Date Filed
June 1, 2023
0Patent Citations
...
Patent Primary Examiner
Patent abstract
Provided herein is a pharmaceutical composition comprising an effective amount of cypate-Cyclo(Cys-Gly-Arg-Asp-Ser-Pro-Cys)-Lys-OH (LS301), cypate-Cyclo(Cys-Gly-Arg-Asp-Ser-Pro-Cys)-Tyr-OH (LS838) or pharmaceutically acceptable salts thereof, wherein each amino acid residue is independently in a D or L configuration; a divalent metal ion; and a pharmaceutically acceptable carrier. Further provided are lyophilized products comprising a dye-conjugate and m methods for identifying compromised and for binding phosphorylated annexin A2 (pANXA2) protein in a biological sample using a composition described herein.
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