US Patent 12127537 Genetically modified non-human animals and methods of use thereof

Is a

Patent

Patent attributes

Current Assignee

Regeneron Pharmaceuticals

Patent Jurisdiction

United States Patent and Trademark Office

Patent Number

121275370

Patent Inventor Names

Andrew J. Murphy0

Till Strowig0

George Yancopoulos0

Markus Manz0

Anthony Rongvaux0

Tim Willinger0

Richard Flavell0

Sean Stevens0

Date of Patent

October 29, 2024

Patent Application Number

173162660

Date Filed

May 10, 2021

Patent Citations

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US Patent 8847004 Humanized M-CSF mice

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US Patent 8878001 Humanized IL-6 and IL-6 receptor

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US Patent 9127292 Non-human animals having a humanized signal-regulatory protein gene

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US Patent 9155290 Humanized IL-15 animals

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US Patent 9193977 Non-human animals having a humanized signal-regulatory protein gene

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US Patent 9301509 Genetically modified mice and engraftment

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Patent Primary Examiner

CPC Code

...

Patent abstract

The invention relates generally to genetically modified non-human animals expressing human polypeptides and their methods of use.

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US Patent 12127537 Genetically modified non-human animals and methods of use thereof

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