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US Patent 12128100 Immunogenic compositions for treatment of Hepatitis B

Patent 12128100 was granted and assigned to Variation Biotechnologies on October, 2024 by the United States Patent and Trademark Office.

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Is a
Patent
Patent
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Patent attributes

Patent Applicant
Variation Biotechnologies
Variation Biotechnologies
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Current Assignee
Variation Biotechnologies
Variation Biotechnologies
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
121281000
Patent Inventor Names
David Evander Anderson0
Tanvir Ahmed0
Date of Patent
October 29, 2024
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Patent Application Number
172934310
Date Filed
November 13, 2019
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Patent Primary Examiner
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Barry A Chestnut
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CPC Code
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A61K 2039/57
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A61K 39/292
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A61K 2039/505
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A61K 39/12
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Patent abstract

The present disclosure provides compositions and methods useful for inducing a The cell response in a subject suffering from Hepatitis B. As described herein, the compositions of the disclosure comprise HBsAg having S, Pre-S1 and Pre-S2 proteins and an aluminum phosphate adjuvant. In a preferred embodiment, the immunogenic composition comprises at least 20 μg/ml of HBsAg antigen and the amount of non-adsorbed antigen is at least 30%.

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