US Patent 12128166 Systems and methods for using nitric oxide in dialysis

A hemodiafiltration (HDF) system is provided for performing HDF treatment. The HDF system includes a mixing system for mixing nitric oxide (NO) with other chemicals to produce a dialysis fluid. The HDF system further includes an extracorporeal blood circuit that includes a filter for separating the dialysis fluid into a dialysate and NO spiked substitution fluid. The extracorporeal blood circuit also includes a dialyzer that receives the dialysate and a blood line connected to the dialyzer. The blood line includes admission points connected to the filter. The admission points are used to administer the NO spiked substitution fluid to the patient during the HDF treatment.