Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Maryna V. Ivanchenko0
Killian S. Hanlon0
Casey A. Maguire0
David P. Corey0
Date of Patent
October 29, 2024
0Patent Application Number
174745350
Date Filed
September 14, 2021
0Patent Citations
Patent Primary Examiner
Patent abstract
Aspects of the disclosure relate to compositions and methods for treating hereditary hearing loss and/or vision loss, for example, due to Usher syndrome, Type 3A. In some embodiments, the disclosure provides a recombinant adeno-associated virus comprising: (i) an AAV-S capsid protein, and (ii) an isolated nucleic acid comprising a transgene (e.g., a transgene for expressing a clarin-1 protein). The present disclosure also provides methods of treating hereditary hearing loss and/or vision loss (e.g., Usher Syndrome, Type 3A) using the same.
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