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US Patent 12134630 Compositions and methods for liquid phase oligonucleotide synthesis

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Is a

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Patent attributes

Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

Yun-Chiao Yao0

David Yu0

Aldrich N.K. Lau0

Jingshe Song0

Shengdong Wang0

Hongrong Yang0

Gaomai Yang0

Date of Patent

November 5, 2024

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Patent Application Number

183372330

Date Filed

June 19, 2023

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Patent Citations

US Patent 8664357 Solvent resistant diafiltration of peptides, PNA or oligonucleotides

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US Patent 8450504 Polymers bearing pendant pentafluorophenyl ester groups, and methods of synthesis and functionalization thereof

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US Patent 10544456 Systems and methods for nucleic acid sequencing

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US Patent 7276599 Oligonucleotide synthesis with alternative solvents

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US Patent 8143369 Polymers bearing pendant pentafluorophenyl ester groups, and methods of synthesis and functionalization thereof

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Patent Primary Examiner

Robert D Harlan

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CPC Code

0

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Patent abstract

Embodiments of the present application relate to polymers used as polymeric polyvalent hubs for liquid phase oligonucleotide synthesis. Methods for making an oligonucleotide by liquid phase oligonucleotide synthesis using the polymers are also provided.

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