Patent 12134767 was granted and assigned to Vertex Pharmaceuticals on November, 2024 by the United States Patent and Trademark Office.
The present application provides materials and methods for treating hemoglobinopathies. More specifically, the application provides methods for producing progenitor cells that are genetically modified via genome editing to increase the production of fetal hemoglobin (HbF), as well as modified progenitor cells (including, for example, CD34