US Patent 6846652 Viral vectors having enhanced effectiveness with reduced virulence
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Patent abstract
The present invention provides methods of use of recombinant vaccinia virus from which the region encoding the N-terminal 83 or 54 amino acids of the E3L gene product has been deleted, or amino acids at positions 44 and 66 have been mutated. Compositions comprising the recombinant vaccinia virus are also provided.
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Patent Inventor Names
Bertram Jacobs0
Teresa A. Brandt0
Date of Patent
January 25, 2005
0Patent Application Number
098872950
Date Filed
June 22, 2001
0Patent Primary Examiner
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US Patent 6846652 Viral vectors having enhanced effectiveness with reduced virulence
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