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US Patent 6852855 Synthesis of piperazine ring

Patent 6852855 was granted and assigned to Teva Pharmaceutical Industries on February, 2005 by the United States Patent and Trademark Office.

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Patent Applicant
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Current Assignee
Teva Pharmaceutical Industries
Teva Pharmaceutical Industries
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
68528550
Patent Inventor Names
Ben-Zion Dolitzky0
Date of Patent
February 8, 2005
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Patent Application Number
099394060
Date Filed
August 24, 2001
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Patent Primary Examiner
Emily Bernhardt
Emily Bernhardt
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Patent abstract

A novel process for preparing a compound of the formula I:whereinR1 denotes substituted or unsubstituted alkyl, alkoxy, aryl, aryloxy or arylalkoxy; R2 denotes substituted or unsubstituted alkyl, alkoxy, aryl, aryloxy, arylalkoxy, tosyl, formyl, acetyl or amine; and R3 denotes substituted or unsubstituted alkyl, alkoxy, aryl, aryloxy or arylalkoxy is disclosed. These compounds are useful in the synthesis of the antidepressant mirtazapine and other tetracyclic compounds.

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