Is a
Patent attributes
Patent Applicant
0
Patent Jurisdiction
Patent Number
Patent Inventor Names
Alexandra C. McPherron0
Se-Jin Lee0
Date of Patent
February 22, 2005
0Patent Application Number
102788030
Date Filed
October 22, 2002
0Patent Citations Received
Patent Primary Examiner
Patent abstract
A transgenic non-human animal of the species selected from the group consisting of avian, bovine, ovine and porcine having a transgene which results in disrupting the production of and/or activity of growth differentiation factor-8 (GDF-8) chromosomally integrated into the germ cells of the animal is disclosed. Also disclosed are methods for making such animals, and methods of treating animals with antibodies or antisense directed to GDF-8. The animals so treated are characterized by increased muscle tissue.
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