A laboratory tote, formed from a single sheet of corrugated polymeric material, includes a receptacle portion defined by a bottom wall and respective end walls and sidewalls hingedly joined to opposing edges of the bottom wall. A handle extends between the sidewalls and above the receptacle to facilitate placement and removal of items into and out of the receptacle. The tote may be provided with a variety of partitions formed from separate removable components and configured to divide the receptacle into compartments of varying size, as desired.