Is a
Patent attributes
Patent Applicant
0
Patent Jurisdiction
Patent Number
Patent Inventor Names
Muthiah Manoharan0
Yogesh S. Sanghvi0
Date of Patent
March 15, 2005
0Patent Application Number
094389890
Date Filed
November 12, 1999
0Patent Citations Received
Patent Primary Examiner
Patent abstract
Novel chiral compounds that mimic and/or modulate the activity of wild-type nucleic acids are disclosed. In general, the compounds are phosphorothioate oligonucleotides wherein the 5′, and the 3′-terminal internucleoside linkages are chirally Sp and internal internucleoside linkages are chirally Rp.
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