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US Patent 6939548 Methods to produce high levels of C. difficile toxins

Patent 6939548 was granted and assigned to Techlab, Inc. on September, 2005 by the United States Patent and Trademark Office.

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Patent abstract

The present invention relates to the field of medical immunology and further to pharmaceutical compositions, methods of making and methods of use of vaccines. More specifically this invention relates to recombinant proteins derived from the genes encoding Clostridium difficile toxin A and toxin B, and their use in an active vaccine against C. difficile.

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