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US Patent 6962991 Process for the synthesis of pyrazolopyrimidines

Patent 6962991 was granted and assigned to EPOCH BIOSCIENCES, INC. on November, 2005 by the United States Patent and Trademark Office.

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Patent abstract

The present invention provides a nucleoside comprising a pyrazolopyrimidine base and a process for producing the same. In particular, the processes of the present invention comprises using a halogenated pyrazolopyrimidine base and removing the halogen after the base is coupled to a sugar moiety. The presence of the halogen on the nucleoside base allows facile and economical production of a large quantity of nucleosides.

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