US Patent 6969850 Microfluidic array devices and methods of manufacturing and uses thereof

Microfluidic nozzle array devices are provided with the body of each device having at least one nozzle extending outwardly from one surface of the body. Each nozzle includes a tip opening having a diameter of equal to or less than about 100 μm, preferably 50 μm, and more preferably 20 μm and an outer diameter of nozzle is equal to or less than about 150 μm, preferably 100 μm, and more preferably 50 μm. The microfluidic nozzle array devices are fabricated using an injection molding process and find particular utility in a wide range of applications, including but not limited to nanospray/electrospray applications, mass spectrometer applications, optical spectrometry applications, spotting applications (i.e., DNA or protein array), etc.